Mail: [email protected]
Tél: +33649290734
Docteur en Biologie moléculaire, Robert Bunet est chercheur à l’Institut océanographique depuis 2014 où il travaille au développement de méthodes d’évaluation de l’efficacité antifouling de substances naturelles issues du milieu marin. Il s’intéresse également aux traces d’ADN laissées par les organismes dans leur environnement, comme moyen de détection et de suivi de la biodiversité marine. Ses recherches antérieures ont participé à la compréhension des mécanismes de régulation de la synthèse d’antibiotiques chez les bactéries et à la production de nouveaux composés thérapeutiques par des approches de génie génétique.
PUBLICATIONS
Réveillon D., A. Tunin-Ley, I. Grondin, A. Othmani, M. Zubia, R. BUNET, J. Turquet, G. CULiOLI, J.F. Briand, 2018 (Submitted) – Exploiting the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds. J. appl. Phycol.
BUNET R., J.F. BRIAND, J.L. BONNEFONT, 2016 – Developing new methods to evaluate anti-macrofouling efficacy of natural compounds and textured surfaces. Poster, 18th International Congress on Marine Corrosion and Fouling – ICMCF 2016. June 19-24, 2016 at Toulon, France.
OTHMANI A., R. BUNET, J.L. BONNEFONT, J.F. BRIAND, G. CULIOLI, 2016 – Settlement inhibition of marine biofilm bacteria and barnacle larvae by compounds isolated from the Mediterranean brown alga Taonia atomaria. J. appl. Phycol., 28 : 1975-1986.
COUVRAY S., T. MIARD, R. BUNET, Y. MARTIN, J.P. GRILLASCA, J.L. BONNEFONT, S. COUPÉ, 2015 – Experimental release of Paracentrotus lividus sea urchin juveniles in exploited sites along the French Mediterranean coast. J. Shellfish Res., 34 (2) : 1-9.
Bunet R, R. Riclea, L. Laureti, L. Hôtel, C. Paris, J.M. Girardet, D. Spiteller, J.S. Dickschat, P. Leblond, B. Aigle, 2014 – A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877. PLoS One, Jan 31;9(1).
Richard S, N. Prévot-D’Alvise, R. Bunet, R. Simide, S. Couvray, S. Coupé, J.P. GRILLASCA, 2014 – Effect of a glyphosate-based herbicide on gene expressions of the cytokines interleukin-1β and interleukin-10 and of heme oxygenase-1 in European sea bass, Dicentrarchus labrax L. Bull Environ Contam Toxicol, Mar 92(3):294-9.
Prevot-D’Alvise N, S. Richard, S. Coupé, R. Bunet, J.P. Grillasca, 2013 – Acute toxicity of a commercial glyphosate formulation on European sea bass juveniles (Dicentrarchus labrax L.): gene expressions of heme oxygenase-1 (ho-1), acetylcholinesterase (AChE) and aromatases (cyp19a and cyp19b). Cell Mol Biol (Noisy-le-grand), Dec 31;59.
Gottelt M, A. Hesketh, R. Bunet, P. Puri, E. Takano. 2012 – Characterisation of a natural variant of the γ-butyrolactone signalling receptor. BMC Res Notes, Jul 27;5:379.
Bunet R, Song L, Mendes MV, Corre C, Hotel L, Rouhier N, Framboisier X, Leblond P, Challis GL, Aigle B. 2011 – Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins. J Bacteriol., Mar;193(5):1142-53.
Aigle B, Bunet R, Corre C, Garenaux A, Huang S, Laureti L, Lautru S, Mendes MV, Nezbedová S, Nguyen HC, Song L, Weiser J, Challis GL, Leblond P, JL Pernodet. 2011 – Genome-guided Exploration of Streptomyces ambofaciens Secondary Metabolism. Streptomyces: Molecular Biology and Biotechnology.
Hsiao NH, Nakayama S, Merlo ME, de Vries M, Bunet R, Kitani S, Nihira T, Takano E. 2009 – Analysis of two additional signaling molecules in Streptomyces coelicolor and the development of a butyrolactone-specific reporter system. Chem Biol., Sep 25;16(9):951-60.
Bunet R, Mendes MV, Rouhier N, Pang X, Hotel L, Leblond P, Aigle B. 2008 – Regulation of the synthesis of the angucyclinone antibiotic alpomycin in Streptomyces ambofaciens by the autoregulator receptor AlpZ and its specific ligand. J Bacteriol, May;190(9):3293-305.
Bunet R, Brock A, Rexer HU, Takano E. 2006 – Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2). FEMS Microbiol Lett., Sep;262(1):57-64.
Roth V, Aigle B, Bunet R, Wenner T, Fourrier C, Decaris B, Leblond P. 2004 – Differential and cross-transcriptional control of duplicated genes encoding alternative sigma factors in Streptomyces ambofaciens. J Bacteriol., Aug;186(16):5355-65.